MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

Abstract Background The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogen...

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Bibliographic Details
Main Authors: Stefanie Friedrich, Remus Barbulescu, Thomas Helleday, Erik L. L. Sonnhammer
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Medical Genomics
Subjects:
Human genome analysis
Copy number calling
Low coverage data
Online Access:http://link.springer.com/article/10.1186/s12920-020-00731-y

Internet

http://link.springer.com/article/10.1186/s12920-020-00731-y

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