MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data
Abstract Background The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a tissue sample, e.g. a cancerous area in a heterogen...
Main Authors: | Stefanie Friedrich, Remus Barbulescu, Thomas Helleday, Erik L. L. Sonnhammer |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12920-020-00731-y |
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