Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae

Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae

Abstract Background Susceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses. Despite the fact that some of these mutations are known to introduce non-synonymous substitutions...

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Bibliographic Details
Main Authors: Ashley A Brenton, Lattha Souvannaseng, Kong Cheung, Michael Anishchenko, Aaron C Brault, Shirley Luckhart
Format: Article
Language:English
Published: BMC 2014-06-01
Series:Parasites & Vectors
Subjects:
Anopheles
Mosquito
MAPK
Plasmodium
Malaria
Single nucleotide polymorphism
Online Access:https://doi.org/10.1186/1756-3305-7-287

Internet

https://doi.org/10.1186/1756-3305-7-287

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