Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation

Background: Atrial Fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, responsible for considerable morbidity and mortality. The heterogenic and complex pathogenesis of AF remains poorly understood, which contributes to the current limitation in effective treatments. We aimed to id...

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Main Authors: Oliver Bundgaard Vad, Yannan Yan, Federico Denti, Gustav Ahlberg, Lena Refsgaard, Sofia Hammami Bomholtz, Joana Larupa Santos, Simon Rasmussen, Stig Haunsø, Jesper Hastrup Svendsen, Ingrid Elizabeth Christophersen, Nicole Schmitt, Morten Salling Olesen, Bo Hjorth Bentzen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.806429/full