Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

Abstract Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. Methods In the present study we used mass spectrometry-based proteomics in order t...

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Bibliographic Details
Main Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Tarig Al-Hadi Osman, Hans-Peter Marti, Frode Berven, Bjørn Egil Vikse
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Nephrology
Subjects:
IgA nephropathy
Glomerulonephritis
Proteomics
ESRD
Online Access:http://link.springer.com/article/10.1186/s12882-019-1598-1

Internet

http://link.springer.com/article/10.1186/s12882-019-1598-1

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