Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no effective treatment that is caused by the loss of dystrophin. Human induced pluripotent stem cells (hiPSCs) offer a promising unlimited resource for cell-based therapies of muscular dystrophy. Ho...

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Bibliographic Details
Main Authors: Ruojie He, Huan Li, Liang Wang, Yaqin Li, Yu Zhang, Menglong Chen, Yuling Zhu, Cheng Zhang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Biological Research
Subjects:
Duchenne muscular dystrophy
Human induced pluripotent stem cells
Myogenic progenitors
Muscle regeneration
Satellite cells
Online Access:http://link.springer.com/article/10.1186/s40659-020-00288-1

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http://link.springer.com/article/10.1186/s40659-020-00288-1

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