What Do We Know about the Microbiome in Cystic Fibrosis? Is There a Role for Probiotics and Prebiotics?

Cystic fibrosis (CF) is a life-shortening genetic disorder that affects the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In the gastrointestinal (GI) tract, CFTR dysfunction results in low intestinal pH, thick and inspissated mucus, a lack of endogenous pancreatic enzymes, and...

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Bibliographic Details
Main Authors: Josie M. van Dorst, Rachel Y. Tam, Chee Y. Ooi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/3/480