TNFα promotes oral cancer growth, pain, and Schwann cell activation
Abstract Oral cancer is very painful and impairs a patient’s ability to eat, talk, and drink. Mediators secreted from oral cancer can excite and sensitize sensory neurons inducing pain. Cancer mediators can also activate Schwann cells, the peripheral glia that regulates neuronal function and repair....
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-81500-4 |