Aberrant expression of histone deacetylase 8 in endometriosis and its potential as a therapeutic target

Abstract Purpose To screen Zn2+‐dependent histone deacetylase (HDAC) 1‐11 in endometriotic cells and then evaluated the HDACs identified from the screening in ovarian endometrioma (OE) and deep endometriotic (DE) lesions, and to evaluate the therapeutic potential of HDAC8 inhibition in mice. Methods...

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Bibliographic Details
Main Authors: Hanxi Zheng, Xishi Liu, Sun‐Wei Guo
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12531