Aberrant expression of histone deacetylase 8 in endometriosis and its potential as a therapeutic target
Abstract Purpose To screen Zn2+‐dependent histone deacetylase (HDAC) 1‐11 in endometriotic cells and then evaluated the HDACs identified from the screening in ovarian endometrioma (OE) and deep endometriotic (DE) lesions, and to evaluate the therapeutic potential of HDAC8 inhibition in mice. Methods...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Reproductive Medicine and Biology |
Subjects: | |
Online Access: | https://doi.org/10.1002/rmb2.12531 |