Detection of FLT3 Oncogene Mutations in Acute Myeloid Leukemia Using Conformation Sensitive Gel Electrophoresis

Detection of FLT3 Oncogene Mutations in Acute Myeloid Leukemia Using Conformation Sensitive Gel Electrophoresis

FLT3 (fms-related tyrosine kinase 3) is a receptor tyrosine kinase class III that is expressed on by early hematopoietic progenitor cells and plays an important role in hematopoietic stem cell proliferation, differentiation and survival. FLT3 is also expressed on leukemia blasts in most cases of acu...

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Bibliographic Details
Main Authors: Mamdooh Gari, Adel Abuzenadah, Mohammed Al-Qahtani, Adeel Chaudhary, Huda Banni, Waseem Ahmad, Ghazi Damanhouri, Sahira Lary, Fatin Al-Sayes
Format: Article
Language:English
Published: MDPI AG 2008-11-01
Series:International Journal of Molecular Sciences
Subjects:
AML
Flt3
ITD
CSGE
Mutational analysis
Online Access:http://www.mdpi.com/1422-0067/9/11/2194/

Internet

http://www.mdpi.com/1422-0067/9/11/2194/

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