Deficiency in FTSJ1 Affects Neuronal Plasticity in the Hippocampal Formation of Mice

Deficiency in FTSJ1 Affects Neuronal Plasticity in the Hippocampal Formation of Mice

The role of the tRNA methyltransferase FTSJ1 in the brain is largely unknown. We analyzed whether FTSJ1-deficient mice (KO) displayed altered neuronal plasticity. We explored open field behavior (10 KO mice (aged 22–25 weeks)) and 11 age-matched control littermates (WT) and examined mean layer thick...

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Bibliographic Details
Main Authors: Viola von Bohlen und Halbach, Simone Venz, Simon Nwakor, Christian Hentschker, Elke Hammer, Heike Junker, Andreas W. Kuss, Oliver von Bohlen und Halbach, Lars R. Jensen
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biology
Subjects:
FTSJ1
long-term potentiation
tRNA methyl transferase
neuronal plasticity
proteomics
Online Access:https://www.mdpi.com/2079-7737/11/7/1011

Internet

https://www.mdpi.com/2079-7737/11/7/1011

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