Malonic Acid as A Green and Efficient Catalyst for the Mass-scale Synthesis of Pyrrole Medicinal Drugs
A green and naturally biodegradable malonic acid synthesis of highly substituted dihydro-2-oxopyrrole derivatives has been accomplished viaone-pot four-condensation of amines (aromatic or aliphatic), dialkyl acetylenedicarboxylate, and formaldehyde under mild reaction conditions. The notable a...
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| Format: | Article |
| Language: | English |
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Universitas Indonesia
2020-09-01
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| Series: | Makara Journal of Science |
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| Online Access: | https://scholarhub.ui.ac.id/cgi/viewcontent.cgi?article=1203&context=science |