Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease

Membrane transporters enable efficient cellular metabolism, aid in nutrient sensing, and have been associated with various diseases, such as obesity and cancer. Genome-scale metabolic network reconstructions capture genomic, physiological, and biochemical knowledge of a target organism, along with a...

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Bibliographic Details
Main Authors: Swagatika eSahoo, Maike Kathrin Aurich, Jon Johannes Jonsson, Ines eThiele
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00091/full