Targeting Tat–TAR RNA Interaction for HIV-1 Inhibition
The HIV-1 Tat protein interacts with TAR RNA and recruits CDK9/cyclin T1 and other host factors to induce HIV-1 transcription. Thus, Tat–TAR RNA interaction, which is unique for HIV-1, represents an attractive target for anti-HIV-1 therapeutics. To target Tat–TAR RNA interaction, we used a crystal s...
| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
MDPI AG
2021-10-01
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| coleção: | Viruses |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1999-4915/13/10/2004 |