Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Water and Sodium Metabolism

Sodium-glucose cotransporter 2 (SGLT2) inhibitors exert hypoglycemic and diuretic effects by inhibiting the absorption of sodium and glucose from the proximal tubule. Currently available data indicate that SGLT2 inhibitors transiently enhance urinary sodium excretion and urinary volume. When combine...

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Bibliographic Details
Main Authors: Jun Tang, Lifang Ye, Qiqi Yan, Xin Zhang, Lihong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.800490/full