Population monitoring of trisomy 21: problems and approaches

Population monitoring of trisomy 21: problems and approaches

Abstract Trisomy 21 (Down syndrome) is the most common autosomal aneuploidy among newborns. About 90% result from meiotic nondisjunction during oogenesis, which occurs around conception, when also the most profound epigenetic modifications take place. Thus, maternal meiosis is an error prone process...

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Bibliographic Details
Main Authors: Karl Sperling, Hagen Scherb, Heidemarie Neitzel
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Molecular Cytogenetics
Subjects:
Down syndrome
Trisomy 21
Aneuploidy
Epidemiology
Risk factors
Preventive medicine
Online Access:https://doi.org/10.1186/s13039-023-00637-1

Internet

https://doi.org/10.1186/s13039-023-00637-1

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