Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

Single cell RNA sequencing is a powerful tool for understanding cellular diversity but is limited by cost, throughput and sample preparation. Here the authors use nanogrid technology with integrated imaging to sequence thousands of cancer nuclei in parallel from fresh or frozen tissue.

Bibliographic Details
Main Authors: Ruli Gao, Charissa Kim, Emi Sei, Theodoros Foukakis, Nicola Crosetto, Leong-Keat Chan, Maithreyan Srinivasan, Hong Zhang, Funda Meric-Bernstam, Nicholas Navin
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00244-w

Internet

https://doi.org/10.1038/s41467-017-00244-w

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