Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
Single cell RNA sequencing is a powerful tool for understanding cellular diversity but is limited by cost, throughput and sample preparation. Here the authors use nanogrid technology with integrated imaging to sequence thousands of cancer nuclei in parallel from fresh or frozen tissue.
Main Authors: | Ruli Gao, Charissa Kim, Emi Sei, Theodoros Foukakis, Nicola Crosetto, Leong-Keat Chan, Maithreyan Srinivasan, Hong Zhang, Funda Meric-Bernstam, Nicholas Navin |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-08-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00244-w |
Similar Items
-
Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing
by: Jake Leighton, et al.
Published: (2023-01-01) -
SENTINEL LYMPH NODE DISSECTION CONTROVERSIES
by: Funda Meriç Bernstam
Published: (2005-01-01) -
BREAST CONSERVING SURGERY IN LOCALLY ADVANCED BREAST CANCER
by: Funda Meriç Bernstam
Published: (2006-01-01) -
BREAST-CONSERVING THERAPY
by: Funda Meriç Bernstam
Published: (2005-01-01) -
Analysis of Smart Loads in Nanogrids
by: Mohsen S. Pilehvar, et al.
Published: (2019-01-01)