Ethylenediamine Salt Enhances the Solubility and Dissolution of Flurbiprofen

Abstract Drugs that are poorly soluble in water are difficult to absorb orally, resulting in low bioavailability. Flurbiprofen (FLU) is an arylpropionic acid nonsteroidal anti‐inflammatory drug belonging to BCS class II, with low water solubility. In this study, a novel flurbiprofen‐ethylenediamine...

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Bibliographic Details
Main Authors: Dr. Lei Gao, Xiaojie Li, Xiaolin Yan, Dr. Xianrui Zhang
Format: Article
Language:English
Published: Wiley-VCH 2024-06-01
Series:ChemistryOpen
Subjects:
Online Access:https://doi.org/10.1002/open.202300262