Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts

We tested the hypothesis that single-cell RNA-sequencing (scRNA-seq) analysis of human kidney allograft biopsies will reveal distinct cell types and states and yield insights to decipher the complex heterogeneity of alloimmune injury. We selected 3 biopsies of kidney cortex from 3 individuals for sc...

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Bibliographic Details
Main Authors: Hemant Suryawanshi, Hua Yang, Michelle Lubetzky, Pavel Morozov, Mila Lagman, Gaurav Thareja, Alicia Alonso, Carol Li, Catherine Snopkowski, Aziz Belkadi, Franco B. Mueller, John R. Lee, Darshana M. Dadhania, Steven P. Salvatore, Surya V. Seshan, Vijay K. Sharma, Karsten Suhre, Manikkam Suthanthiran, Thomas Tuschl, Thangamani Muthukumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165878/?tool=EBI