DNA-triggered aggregation of copper, zinc superoxide dismutase in the presence of ascorbate.

The oxidative damage hypothesis proposed for the function gain of copper, zinc superoxide dismutase (SOD1) maintains that both mutant and wild-type (WT) SOD1 catalyze reactions with abnormal substrates that damage cellular components critical for viability of the affected cells. However, whether the...

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Bibliographic Details
Main Authors: Jun Yin, Si Hu, Wei Jiang, Liang Liu, Shemin Lan, Xuegang Song, Changlin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20808835/pdf/?tool=EBI