Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor

Abstract The endogenous fatty acid amide palmitoylethanolamide (PEA) has been shown to exert anti-inflammatory actions mainly through inhibition of the release of pro-inflammatory molecules from mast cells, monocytes and macrophages. Indirect activation of the endocannabinoid (eCB) system is among t...

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Bibliographic Details
Main Authors: F. Guida, L. Luongo, S. Boccella, M. E. Giordano, R. Romano, G. Bellini, I. Manzo, A. Furiano, A. Rizzo, R. Imperatore, F. A. Iannotti, E. D’Aniello, F. Piscitelli, F. sca Rossi, L. Cristino, V. Di Marzo, V. de Novellis, S. Maione
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00342-1