Gamma Interferon Is Required for <italic toggle="yes">Chlamydia</italic> Clearance but Is Dispensable for T Cell Homing to the Genital Tract

ABSTRACT While there is no effective vaccine against Chlamydia trachomatis infection, previous work has demonstrated the importance of C. trachomatis-specific CD4+ T cells (NR1 T cells) in pathogen clearance. Specifically, NR1 T cells have been shown to be protective in mice, and this protection dep...

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Bibliographic Details
Main Authors: Jennifer D. Helble, Rodrigo J. Gonzalez, Ulrich H. von Andrian, Michael N. Starnbach
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00191-20