The Outside-In Journey of Tissue Transglutaminase in Cancer
Tissue transglutaminase (TG2) is a member of the transglutaminase family that catalyzes Ca<sup>2+</sup>-dependent protein crosslinks and hydrolyzes guanosine 5′-triphosphate (GTP). The conformation and functions of TG2 are regulated by Ca<sup>2+</sup> and GTP levels; the TG2...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/11/1779 |