The Outside-In Journey of Tissue Transglutaminase in Cancer

Tissue transglutaminase (TG2) is a member of the transglutaminase family that catalyzes Ca<sup>2+</sup>-dependent protein crosslinks and hydrolyzes guanosine 5′-triphosphate (GTP). The conformation and functions of TG2 are regulated by Ca<sup>2+</sup> and GTP levels; the TG2...

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Bibliographic Details
Main Authors: Livia Elena Sima, Daniela Matei, Salvatore Condello
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/11/1779