Reconstitution reveals two paths of force transmission through the kinetochore

Partitioning duplicated chromosomes equally between daughter cells is a microtubule-mediated process essential to eukaryotic life. A multi-protein machine, the kinetochore, drives chromosome segregation by coupling the chromosomes to dynamic microtubule tips, even as the tips grow and shrink through...

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Bibliographic Details
Main Authors: Grace E Hamilton, Luke A Helgeson, Cameron L Noland, Charles L Asbury, Yoana N Dimitrova, Trisha N Davis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/56582