IgE and IgG4 epitopes of the peanut allergens shift following oral immunotherapy

IgE and IgG4 epitopes of the peanut allergens shift following oral immunotherapy

BackgroundOral immunotherapy (OIT) with peanut (Arachis hypogaea) allergen powder-dnfp (PTAH; Aimmune Therapeutics) is an FDA-approved treatment to desensitize peanut allergic participants.ObjectiveHere we assessed shifts in IgE and IgG4 binding to peanut allergens and their epitopes recognized by U...

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Bibliographic Details
Main Authors: Ian M. Rambo, Christina M. Kronfel, Adam R. Rivers, Lauren T. Swientoniewski, Jane K. McBride, Hsiaopo Cheng, Reyna J. Simon, Robert Ryan, Stephen A. Tilles, Jacqueline B. Nesbit, Michael D. Kulis, Barry K. Hurlburt, Soheila J. Maleki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Allergy
Subjects:
peanut allergy
epitope
immunoglobulin
oral immunotherapy
microarray
ISAC
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2023.1279290/full

Internet

https://www.frontiersin.org/articles/10.3389/falgy.2023.1279290/full

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