In situ nuclear DNA methylation in dilated cardiomyopathy: an endomyocardial biopsy study

In situ nuclear DNA methylation in dilated cardiomyopathy: an endomyocardial biopsy study

Abstract Aims Although distinct DNA methylation patterns have been reported, its localization and roles remain to be defined in heart failure. We investigated the cellular and subcellular localization of DNA methylation and its pathophysiological significance in human failing hearts. Methods and res...

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Bibliographic Details
Main Authors: Takatomo Watanabe, Hideshi Okada, Hiromitsu Kanamori, Nagisa Miyazaki, Akiko Tsujimoto, Chihiro Takada, Kodai Suzuki, Genki Naruse, Akihiro Yoshida, Takahide Nawa, Toshiki Tanaka, Masanori Kawasaki, Hiroyasu Ito, Shinji Ogura, Hiroyuki Okura, Takako Fujiwara, Hisayoshi Fujiwara, Genzou Takemura
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:ESC Heart Failure
Subjects:
Chromatin remodelling
Dilated cardiomyopathy
DNA methylation, Epigenetics
Online Access:https://doi.org/10.1002/ehf2.12593

Internet

https://doi.org/10.1002/ehf2.12593

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