Facile bead‐to‐bead cell‐transfer method for serial subculture and large‐scale expansion of human mesenchymal stem cells in bioreactors

Facile bead‐to‐bead cell‐transfer method for serial subculture and large‐scale expansion of human mesenchymal stem cells in bioreactors

Abstract The conventional planar culture of adherent cells is inefficient for large‐scale manufacturing of cell and gene therapy products. We developed a facile and efficient bead‐to‐bead cell‐transfer method for serial subculture and large‐scale expansion of human mesenchymal stem cells (hMSCs) wit...

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Bibliographic Details
Main Authors: Shangwu Chen, Yushi Sato, Yasuhiko Tada, Yuma Suzuki, Ryosuke Takahashi, Masahiro Okanojo, Katsuhiko Nakashima
Format: Article
Language:English
Published: Oxford University Press 2021-09-01
Series:Stem Cells Translational Medicine
Subjects:
bead‐to‐bead transfer
bioreactor
mesenchymal stem cell
microcarrier
nucleosides
scale up
Online Access:https://doi.org/10.1002/sctm.20-0501

Internet

https://doi.org/10.1002/sctm.20-0501

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