Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low‐Density Lipoprotein Cholesterol

Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low‐Density Lipoprotein Cholesterol

Background HIV+ people are at increased risk of coronary artery disease, but the responsible mechanisms are incompletely understood. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is traditionally recognized for its importance in cholesterol metabolism; however, recent data suggest an additio...

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Bibliographic Details
Main Authors: Thorsten M. Leucker, Robert G. Weiss, Michael Schär, Gabriele Bonanno, Lena Mathews, Steven R. Jones, Todd T. Brown, Richard Moore, Yohannes Afework, Gary Gerstenblith, Allison G. Hays
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
endothelial function
HIV
inflammation
magnetic resonance
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009996

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.009996

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