Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions

Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions

The unlimited expansion of human progenitor cells in vitro could unlock many prospects for regenerative medicine. However, it remains an important challenge as it requires the decoupling of the mechanisms supporting progenitor self-renewal and expansion from those mechanisms promoting their differen...

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Bibliographic Details
Main Authors: Luka Jarc, Manuj Bandral, Elisa Zanfrini, Mathias Lesche, Vida Kufrin, Raquel Sendra, Daniela Pezzolla, Ioannis Giannios, Shahryar Khattak, Katrin Neumann, Barbara Ludwig, Anthony Gavalas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
hPS cells
pancreas progenitors
signaling
islets
β-cells
differentiation
Online Access:https://elifesciences.org/articles/89962

Internet

https://elifesciences.org/articles/89962

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