Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons

Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons

Summary: Dysfunction of noradrenergic (NA) neurons is associated with a number of neuronal disorders. Diverse neuronal subtypes can be generated by direct reprogramming. However, it is still unknown how to convert non-neuronal cells into NA neurons. Here, we show that seven transcription factors (TF...

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Bibliographic Details
Main Authors: Sanlan Li, Yuhan Shi, Xuan Yao, Xing Wang, Libing Shen, Zhiping Rao, Jiacheng Yuan, Yueguang Liu, Zhenning Zhou, Ziheng Zhang, Fei Liu, Su’e Han, Junlan Geng, Hui Yang, Leping Cheng
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719308150

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http://www.sciencedirect.com/science/article/pii/S2211124719308150

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