Global analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory program.

Global analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory program.

An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae. Neutrophils undergo an aggressive opsonin-independent response to N. gonorrhoeae, driven by the innate decoy receptor CEACAM3. CEACAM3 is exclusively...

Full description

Bibliographic Details
Main Authors: Anna Sintsova, Helen Sarantis, Epshita A Islam, Chun Xiang Sun, Mohsen Amin, Carlos H F Chan, Clifford P Stanners, Michael Glogauer, Scott D Gray-Owen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4154863?pdf=render

Internet

http://europepmc.org/articles/PMC4154863?pdf=render

Similar Items