Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution

Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution

NMR studies of large proteins, over 100 kDa, in solution are technically challenging and, therefore, of considerable interest in the biophysics field. The challenge arises because the molecular tumbling of a protein in solution considerably slows as molecular mass increases, reducing the ability to...

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Bibliographic Details
Main Authors: Tatiana V. Ilina, Zhaoyong Xi, Teresa Brosenitsch, Nicolas Sluis-Cremer, Rieko Ishima
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
HIV
reverse transcriptase
protein
NMR
ribonuclease H
isotope labeling
Online Access:https://www.mdpi.com/1422-0067/21/24/9545

Internet

https://www.mdpi.com/1422-0067/21/24/9545

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