Crowding and confinement act in concert to slow DNA diffusion within cell-sized droplets

Summary: Dynamics of biological macromolecules, such as DNA, in crowded and confined environments are critical to understanding cellular processes such as transcription, infection, and replication. However, the combined effects of cellular confinement and crowding on macromolecular dynamics remain p...

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Bibliographic Details
Main Authors: Mehdi Shafiei Aporvari, Steven Dang, Juexin Marfai, Kara Coursey, Ryan McGorty, Rae M. Robertson-Anderson
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013943