Exploring the effect of network topology, mRNA and protein dynamics on gene regulatory network stability

Maintaining protein expression levels is essential to cellular homeostasis. Here, the authors investigate how transcription factors affect the stability of protein expression in a gene regulatory network, and highlight the importance of network topology.

Bibliographic Details
Main Authors: Yipei Guo, Ariel Amir
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20472-x