Altered Calcium Influx Pathways in Cancer-Associated Fibroblasts

Altered Calcium Influx Pathways in Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAFs) represent an important component of the tumour microenvironment and are implicated in disease progression. Two outstanding questions in cancer biology are how CAFs arise and how they might be targeted therapeutically. The calcium signal also has an important role...

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Bibliographic Details
Main Authors: Francisco Sadras, Teneale A. Stewart, Mélanie Robitaille, Amelia A. Peters, Priyakshi Kalita-de Croft, Patsy S. Soon, Jodi M. Saunus, Sunil R. Lakhani, Sarah J. Roberts-Thomson, Gregory R. Monteith
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
breast cancer
cancer-associated fibroblasts
calcium
calcium signalling
voltage-gated calcium channels
store-operated calcium entry
Online Access:https://www.mdpi.com/2227-9059/9/6/680

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https://www.mdpi.com/2227-9059/9/6/680

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