Inhibitory to non-inhibitory evolution of the ζ subunit of the F1FO-ATPase of Paracoccus denitrificans and α-proteobacteria as related to mitochondrial endosymbiosis

Introduction: The ζ subunit is a potent inhibitor of the F1FO-ATPase of Paracoccus denitrificans (PdF1FO-ATPase) and related α-proteobacteria different from the other two canonical inhibitors of bacterial (ε) and mitochondrial (IF1) F1FO-ATPases. ζ mimics mitochondrial IF1 in its inhibitory N-termin...

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Main Authors: Francisco Mendoza-Hoffmann, Lingyun Yang, Damiano Buratto, Jorge Brito-Sánchez, Gilberto Garduño-Javier, Emiliano Salinas-López, Cristina Uribe-Álvarez, Raquel Ortega, Oliver Sotelo-Serrano, Miguel Ángel Cevallos, Leticia Ramírez-Silva, Salvador Uribe-Carvajal, Gerardo Pérez-Hernández, Heliodoro Celis-Sandoval, José J. García-Trejo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1184200/full