Age-Associated Glia Remodeling and Mitochondrial Dysfunction in Neurodegeneration: Antioxidant Supplementation as a Possible Intervention

Age-Associated Glia Remodeling and Mitochondrial Dysfunction in Neurodegeneration: Antioxidant Supplementation as a Possible Intervention

Aging induces substantial remodeling of glia, including density, morphology, cytokine expression, and phagocytic capacity. Alterations of glial cells, such as hypertrophy of lysosomes, endosomes and peroxisomes, and the progressive accumulation of lipofuscin, lipid droplets, and other debris have al...

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Bibliographic Details
Main Authors: Anna Picca, Evelyn Ferri, Riccardo Calvani, Hélio J. Coelho-Júnior, Emanuele Marzetti, Beatrice Arosio
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nutrients
Subjects:
astrocytes
extracellular vesicles
inflammation
microglia
mitochondrial quality
mitophagy
Online Access:https://www.mdpi.com/2072-6643/14/12/2406

Internet

https://www.mdpi.com/2072-6643/14/12/2406

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