Voltage-Gated Sodium Channels as Potential Biomarkers and Therapeutic Targets for Epithelial Ovarian Cancer

Voltage-Gated Sodium Channels as Potential Biomarkers and Therapeutic Targets for Epithelial Ovarian Cancer

Abnormal ion channel expression distinguishes several types of carcinoma. Here, we explore the relationship between voltage-gated sodium channels (VGSC) and epithelial ovarian cancer (EOC). We find that EOC cell lines express most VGSC, but at lower levels than fallopian tube secretory epithelial ce...

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Bibliographic Details
Main Authors: Iris S. Brummelhuis, Stephen J. Fiascone, Kathleen T. Hasselblatt, Gyorgy Frendl, Kevin M. Elias
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
high-grade serous ovarian cancer
sodium channels
local anesthetics
Online Access:https://www.mdpi.com/2072-6694/13/21/5437

Internet

https://www.mdpi.com/2072-6694/13/21/5437

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