A<sub>2A</sub> Adenosine Receptor: A Possible Therapeutic Target for Alzheimer’s Disease by Regulating NLRP3 Inflammasome Activity?

A<sub>2A</sub> Adenosine Receptor: A Possible Therapeutic Target for Alzheimer’s Disease by Regulating NLRP3 Inflammasome Activity?

The A<sub>2A</sub> adenosine receptor, a member of the P1 purinergic receptor family, plays a crucial role in the pathophysiology of different neurodegenerative illnesses, including Alzheimer’s disease (AD). It regulates both neurons and glial cells, thus modulating synaptic transmission...

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Bibliographic Details
Main Authors: Stefania Merighi, Manuela Nigro, Alessia Travagli, Silvia Pasquini, Pier Andrea Borea, Katia Varani, Fabrizio Vincenzi, Stefania Gessi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
A<sub>2A</sub> receptors
NLRP3 inflammasome
Alzheimer’s disease
memory loss
neurodegeneration
Online Access:https://www.mdpi.com/1422-0067/23/9/5056

Internet

https://www.mdpi.com/1422-0067/23/9/5056

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