Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

(1) Background: Therapeutic blocking of the interaction between programmed death-1 (PD-1) with its ligand PD-L1, an immune checkpoint, is a promising approach to restore the antitumor immune response. Improved clinical outcomes have been shown in different human cancers, including non-small cell lun...

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Bibliographic Details
Main Authors: Eline Berghmans, Julie Jacobs, Christophe Deben, Christophe Hermans, Glenn Broeckx, Evelien Smits, Evelyne Maes, Jo Raskin, Patrick Pauwels, Geert Baggerman
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
mass spectrometry imaging
immunotherapy
non-small cell lung cancer
predictive protein biomarkers
neutrophil defensins
Online Access:https://www.mdpi.com/2072-6694/12/4/863

Internet

https://www.mdpi.com/2072-6694/12/4/863

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