High guanine and cytosine content increases mRNA levels in mammalian cells.

Mammalian genes are highly heterogeneous with respect to their nucleotide composition, but the functional consequences of this heterogeneity are not clear. In the previous studies, weak positive or negative correlations have been found between the silent-site guanine and cytosine (GC) content and ex...

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Bibliographic Details
Main Authors: Grzegorz Kudla, Leszek Lipinski, Fanny Caffin, Aleksandra Helwak, Maciej Zylicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1463026?pdf=render