Impact of R-loops on oncogene-induced replication stress in cancer cells

Replication stress is an alteration in the progression of replication forks caused by a variety of events of endogenous or exogenous origin. In precancerous lesions, this stress is exacerbated by the deregulation of oncogenic pathways, which notably disrupts the coordination between replication and...

Full description

Bibliographic Details
Main Authors: Heuzé, Jonathan, Lin, Yea-Lih, Lengronne, Armelle, Poli, Jérôme, Pasero, Philippe
Format: Article
Language:English
Published: Académie des sciences 2023-09-01
Series:Comptes Rendus Biologies
Subjects:
Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.123/