Impact of R-loops on oncogene-induced replication stress in cancer cells

Replication stress is an alteration in the progression of replication forks caused by a variety of events of endogenous or exogenous origin. In precancerous lesions, this stress is exacerbated by the deregulation of oncogenic pathways, which notably disrupts the coordination between replication and...

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Bibliographic Details
Main Authors: Heuzé, Jonathan, Lin, Yea-Lih, Lengronne, Armelle, Poli, Jérôme, Pasero, Philippe
Format: Article
Language:English
Published: Académie des sciences 2023-09-01
Series:Comptes Rendus Biologies
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Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.123/

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