PI3K/Akt signaling pathway modulates influenza virus induced mouse alveolar macrophage polarization to M1/M2b.

PI3K/Akt signaling pathway modulates influenza virus induced mouse alveolar macrophage polarization to M1/M2b.

Macrophages polarized to M1 (pro-inflammation) or M2 (anti-inflammation) phenotypes in response to environmental signals. In this study, we examined the polarization of alveolar macrophage (AM), following induction by different influenza virus strains (ST169 (H1N1), ST602 (H3N2) and HKG9 (H9N2)). Ma...

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Bibliographic Details
Main Authors: Xiangfeng Zhao, Jianping Dai, Xuejun Xiao, Liqi Wu, Jun Zeng, Jiangtao Sheng, Jinghua Su, Xiaoxuan Chen, Gefei Wang, Kangsheng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4126709?pdf=render

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http://europepmc.org/articles/PMC4126709?pdf=render

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