Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

Summary: Retinal degeneration is a form of neurodegenerative disease and is the leading cause of vision loss globally. The Toll-like receptors (TLRs) are primary components of the innate immune system involved in signal transduction. Here we show that TLR2 induces complement factors C3 and CFB, the...

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Main Authors: Kelly Mulfaul, Ema Ozaki, Nilisha Fernando, Kiva Brennan, Kathleen R. Chirco, Emma Connolly, Chris Greene, Arvydas Maminishkis, Robert G. Salomon, Mikhail Linetsky, Riccardo Natoli, Robert F. Mullins, Matthew Campbell, Sarah L. Doyle
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300899

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http://www.sciencedirect.com/science/article/pii/S2211124720300899

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