BRET biosensors to study GPCR biology, pharmacology and signal transduction

BRET biosensors to study GPCR biology, pharmacology and signal transduction

Bioluminescence Resonance Energy Transfer (BRET) based biosensors have been extensively used over the last decade to study protein-protein interactions and intracellular signal transduction in living cells. In this review, we discuss the various BRET biosensors that have been developed to investigat...

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Bibliographic Details
Main Authors: Ali eSalahpour, Stefano eEspinoza, Bernard eMasri, Vincent eLam, Lawrence eBarak, Raul R Gainetdinov
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Endocrinology
Subjects:
Arrestins
GPCRs
BRET
cAMP
GRKs
Screening assay
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00105/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00105/full

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