Hepatocyte nuclear factor 4 alpha polymorphisms and the metabolic syndrome in French-Canadian youth.

Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor involved in the regulation of serum glucose and lipid levels. Several HNF4A gene variants have been associated with the risk of developing type 2 diabetes mellitus. However, no study has yet explored its association with insulin res...

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Bibliographic Details
Main Authors: Valérie Marcil, Devendra Amre, Ernest G Seidman, François Boudreau, Fernand P Gendron, Daniel Ménard, Jean François Beaulieu, Daniel Sinnett, Marie Lambert, Emile Levy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4325000?pdf=render