Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells

Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells

Abstract Background Macrophage phenotypes switch from proinflammatory (M1) to anti-inflammatory (M2) following myocardial injury. Implanted stem cells (e.g., induced pluripotent stem cells (iPSCs)) for cardiomyogenesis will inevitably contact the inflammatory environment at the myocardial infarction...

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Bibliographic Details
Main Authors: Canling Long, Rui Guo, Ruijuan Han, Kang Li, Yanbing Wan, Jiqing Xu, Xiaoyu Gong, Yanqiu Zhao, Xinhuang Yao, Jia Liu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell Communication and Signaling
Subjects:
Macrophage
iPSCs
Cardiac differentiation
Inflammation
Online Access:https://doi.org/10.1186/s12964-022-00916-1

Internet

https://doi.org/10.1186/s12964-022-00916-1

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