Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest

Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest

Human oocyte maturation arrest represents one of the severe conditions for female patients with primary infertility. However, the genetic factors underlying this human disease remain largely unknown. The spindle assembly checkpoint (SAC) is an intricate surveillance mechanism that ensures accurate s...

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Bibliographic Details
Main Authors: Lingli Huang, Wenqing Li, Xingxing Dai, Shuai Zhao, Bo Xu, Fengsong Wang, Ren-Tao Jin, Lihua Luo, Limin Wu, Xue Jiang, Yu Cheng, Jiaqi Zou, Caoling Xu, Xianhong Tong, Heng-Yu Fan, Han Zhao, Jianqiang Bao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
MAD2L1BP
meiosis
oocyte maturation arrest
oocyte
Online Access:https://elifesciences.org/articles/85649

Internet

https://elifesciences.org/articles/85649

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